Mite allergen-specific IgE is detectable in bronchial secretions of patients with nonatopic asthma and correlates with mucosal expression of periostin.
نویسندگان
چکیده
From a Université Catholique de Louvain (UCL), Institut de Recherche Experimentale et Clinique (IREC), Pole de Pneumologie, ORL & Dermatologie, Brussels, Belgium; b the Department of Pulmonary Medicine, CHU Sart-Tilman, Liege, IGIGA Research Group, University of Liege, Liege, Belgium; and c the Upper Airway Research Laboratory and Department of Otorhinolaryngology, Ghent University, Ghent, Belgium.
منابع مشابه
Recent Progress in Allergen Immunotherapy
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BACKGROUND The pathophysiology of asthma involves allergic inflammation and remodelling in the airway and airway hyperresponsiveness (AHR) to cholinergic stimuli, but many details of the specific underlying cellular and molecular mechanisms remain unknown. Periostin is a matricellular protein with roles in tissue repair following injury in both the skin and heart. It has recently been shown to ...
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BACKGROUND The relationship between mite and pet allergen exposure in infancy and the subsequent development of sensitization and asthma is complex. OBJECTIVE We prospectively investigated the effect of allergen exposure at 3 months of age on the development of sensitization, wheeze, and physician-diagnosed asthma in the first 4 years of life in a birth cohort of children with and without an ...
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ورودعنوان ژورنال:
- The Journal of allergy and clinical immunology
دوره 136 6 شماره
صفحات -
تاریخ انتشار 2015